THE SMART TRICK OF POS88 THAT NO ONE IS DISCUSSING

, 2006; Sawaya and Kraut, 1997; determine 1—figure health supplement one), we envisioned the mutational landscape of DHFR to get constrained by the requirement to adopt these distinctive conformations. What's more, prior operate experienced proposed DHFR is impacted by cellular constraints for example protein excellent control (Bershtein et al.,